Article
Functional characterization of five V2 vasopressin receptor gene mutations.
Molecular and cellular endocrinology - 29 Nov 1996
Wenkert D, Schoneberg T, Merendino J J, Rodriguez Pena M S, Vinitsky R, Goldsmith P K, Wess J, Spiegel A M
Abstract excerpt
COS7 cells were transiently transfected with plasmids encoding mutant forms of the V2 vasopressin receptors corresponding to mutations [Y280C, L292P, R337stop, V277A, and G12E (the latter found in the same kindred with L292P)] recently identified in subjects with X-linked nephrogenic diabetes ins...
Topics
- Animals
- Arginine Vasopressin
- COS Cells
- Cell Membrane
- Cyclic AMP
- Deamino Arginine Vasopressin
- Diabetes Insipidus, Nephrogenic
- Humans
- Kinetics
- Mutation
- Receptors, Vasopressin
- Recombinant Fusion Proteins