Article
Molecular and conformational features of a transport-relevant domain in the C-terminal tail of the vasopressin V(2) receptor.
Molecular pharmacology - 1 Feb 2000
Krause G, Hermosilla R, Oksche A, Rutz C, Rosenthal W, Schülein R
Abstract excerpt
We have previously shown a conserved glutamate/dileucine motif ((335)ELRSLL(340)) in the intracellular C terminus of the vasopressin V(2) receptor (V(2) receptor) to be essential for receptor transport from the endoplasmic reticulum (ER) to the Golgi apparatus. The motif may represent a transport...
Topics
- Amino Acid Sequence
- Biological Transport
- Endoplasmic Reticulum
- Glutamic Acid
- Golgi Apparatus
- Leucine
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Protein Folding
- Receptors, Vasopressin
- Sequence Homology, Amino Acid
- Signal Transduction