Article
Clinical characteristics of Crohn's disease in 72 families.
Gastroenterology - 1 Sept 1996
Colombel J F, Grandbastien B, Gower-Rousseau C, Plegat S, Evrard J P, Dupas J L, Gendre J P, Modigliani R, Bélaïche J, Hostein J, Hugot J P, van Kruiningen H, Cortot A
Abstract excerpt
BACKGROUND & AIMS: Familial aggregation argues for genetic susceptibility to Crohn's disease. The aim of this study was to compare the age of onset and the clinical features of Crohn's disease between patients with familial disease and those with sporadic disease and investigate the concordance for disease location and type among relatives with Crohn's disease. METHODS: Seventy-two families with 2 (n = 55), 3 (n...
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