Article
Familial and sporadic inflammatory bowel disease: different entities?
Inflammatory bowel diseases - 1 Nov 2000
Peeters M, Cortot A, Vermeire S, Colombel J F
Abstract excerpt
The strongest risk factor for developing inflammatory bowel disease (IBD) is having a relative with the disease. Familial IBD may be one homogeneous subgroup, phenotypically different from sporadic IBD. Several observations support a role for familiarity in disease site and behavior, particularly in Crohn's disease (CD), but published findings do not all concur. Early disease onset is often found in children with...
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