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Article

The sequential role of lymphotoxin and B cells in the development of splenic follicles.

The Journal of experimental medicine - 6 Apr 1998

Gonzalez M, Mackay F, Browning J L, Kosco-Vilbois M H, Noelle R J

Abstract excerpt

The transfer of lymphocytes into severe combined immunodeficiency (SCID) mice induces a series of histological changes in the spleen, including the appearance of mature follicular dendritic cells (FDCs). Studies were undertaken to clarify the role of lymphotoxin (LT) in this process. The results show that SCID mice have a small and partially differentiated white pulp containing marginal zone and interdigitating...

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Identifiers

PMID: 9529316
DOI: 10.1084/jem.187.7.997
PMCID: PMC2212214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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