Article
Virological and molecular demonstration of human immunodeficiency virus type 2 vertical transmission.
Journal of virology - 1 Apr 1998
Cavaco-Silva P, Taveira N C, Rosado L, Lourenço M H, Moniz-Pereira J, Douglas N W, Daniels R S, Santos-Ferreira M O
Abstract excerpt
To demonstrate that human immunodeficiency virus type 2 (HIV-2) mother-to-child transmission exists, HIV-2 isolates were obtained from both an asymptomatic mother (HIV-2 strain ARM), and her child (HIV-2 strain SAR), who had a diagnosis of AIDS. To determine their biological phenotype, primary isolates were used to infect various primary mononuclear cells and cell lines. HIV-2 ARM replicates in primary cells and...
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