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Article

Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells.

Journal of virology - 1 Apr 1998

Shtrichman R, Kleinberger T

Abstract excerpt

Adenovirus type 5 E4 open reading frame 4 (E4orf4) protein has been previously shown to counteract transactivation of the junB and c-fos genes by cyclic AMP plus E1A protein and to interact with protein phosphatase 2A (PP2A). Here, we show that the wild-type E4orf4 protein induces apoptosis in the E1A-expressing 293 cells, in NIH 3T3 cells transformed with v-Ras, and in the lung carcinoma cell line H1299. The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9525619
DOI: 10.1128/JVI.72.4.2975-2982.1998
PMCID: PMC109744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells.PMID 9525619Read ↗

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