Article
Apoptosis in thyroid neoplasms: relationship with p53 and bcl-2 expression.
Histopathology - 1 Jan 1998
Moore D, Ohene-Fianko D, Garcia B, Chakrabarti S
Abstract excerpt
AIM: Cell gain and loss occurs concurrently in tumours. Apoptosis may play a major role in determining the growth and aggressiveness of the tumours. The aim of this study was to investigate whether apoptosis is related to the degree of differentiation and expression of mutated p53 and bcl-2 in thyroid neoplasms. METHODS AND RESULTS: Fifty-three thyroid tumours of various histological types and 10 multinodular...
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