Enhanced neutralization of human respiratory syncytial virus by mixtures of monoclonal antibodies to the attachment (G) glycoprotein.

doi:10.1099/0022-1317-79-9-2215

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Article

Enhanced neutralization of human respiratory syncytial virus by mixtures of monoclonal antibodies to the attachment (G) glycoprotein.

The Journal of general virology - 1 Sept 1998

Martínez I, Melero J A

Abstract excerpt

Neutralization of human respiratory syncytial virus (HRSV) by monoclonal antibodies specific for the G protein was evaluated in a microneutralization test. Only certain antibodies showed some degree of neutralization, reflected in a reduction of virus titre (10-20 times maximum), compared with ne...

Topics

Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Epitope Mapping
Epitopes
Glycosylation
HN Protein
Humans
Mutation
Neutralization Tests
Respiratory Syncytial Virus, Human
Viral Envelope Proteins
Viral Proteins

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