Article
Adhesion molecules in breast cancer: role of alpha 2 beta 1 integrin.
Biochemical Society symposium - 1 Jan 1998
Alford D, Pitha-Rowe P, Taylor-Papadimitriou J
Abstract excerpt
An early event in the development of breast carcinomas is the loss of normal tissue architecture. In benign lesions and in situ tumours both luminal and myoepithelial cells are present, but in most invasive cancers the malignant cell has the phenotype of the luminal cell, and proliferates without...
Topics
- Breast Neoplasms
- Cell Adhesion Molecules
- Epithelial Cells
- Female
- Gene Expression Regulation
- Humans
- Integrins
- Phenotype
- Receptors, Collagen