Analysis of the G93E mutant allele of KpsM, the membrane component of an ABC transporter involved in polysialic acid translocation in Escherichia coli K1.

doi:10.1111/j.1574-6968.1997.tb12730.x

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Article

Analysis of the G93E mutant allele of KpsM, the membrane component of an ABC transporter involved in polysialic acid translocation in Escherichia coli K1.

FEMS microbiology letters - 15 Nov 1997

Pigeon R P, Silver R P

Abstract excerpt

KpsM is an integral membrane protein involved in the translocation of the polysialic acid capsule of Escherichia coli K1. The kpsMG93E allele is a point mutation in the first cytoplasmic loop (Cl) of KpsM which partially disrupts translocation of the capsule. While producing polymer of wild-type...

Topics

ATP-Binding Cassette Transporters
Alleles
Antigens, Bacterial
Bacterial Capsules
Biological Transport
Cell Membrane
Escherichia coli
Mutation
Polysaccharides
Polysaccharides, Bacterial
Sialic Acids

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