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Article

Reduced polysialic acid capsule expression in Escherichia coli K1 mutants with chromosomal defects in kpsF.

Molecular microbiology - 1 Oct 1997

Cieslewicz M, Vimr E

Abstract excerpt

Neuroinvasive Escherichia coli K1 synthesizes and assembles a polysialic acid capsule virulence factor on the external leaflet of the outer membrane. This capsule functions in pathogenesis by blocking non-immune host defence mechanisms and acting as a relatively non-immunogenic molecular mimic of the polysialic acid chains found in high concentrations on neural cell adhesion molecules of the human embryo and...

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Source

Identifiers

PMID: 9383150
DOI: 10.1046/j.1365-2958.1997.5651942.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reduced polysialic acid capsule expression in Escherichia coli K1 mutants with chromosomal defects in kpsF.PMID 9383150Read ↗

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