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Article

p53 plays a central role in UVA and UVB induced cell damage and apoptosis in melanoma cells.

Cancer letters - 8 Dec 2006

Zhang Hong

Abstract excerpt

We investigated whether p53 plays a role in UV induced apoptosis in melanoma. UVA and UVB induced apoptosis in dose dependent and wild type p53 melanoma cells were much more vulnerable than the mutant cells, indicating that p53 played a role in UV-induced apoptosis in melanoma. No difference in p53 expression pattern between the primary and matched metastatic melanomas was noticed in tumour tissue or cell lines...

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Identifiers

PMID: 16504377
DOI: 10.1016/j.canlet.2005.12.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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