Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice.

doi:10.1111/j.1399-3089.1998.tb00015.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice.

Xenotransplantation - 1 Feb 1998

Zhao Y, Barth R N, Swenson K, Pearson D A, Sykes M

Abstract excerpt

Mouse CD4+ T cells efficiently develop in fetal pig thymus (FP THY) grafts and repopulate the periphery of T cell and NK cell-depleted, thymectomized (ATX) mice. However, efficient peripheral repopulation of mouse CD8+ T cells does not occur in these mice. We have therefore evaluated the maturati...

Topics

Animals
Antibodies, Monoclonal
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Cell Differentiation
Cytotoxicity, Immunologic
Fetal Tissue Transplantation
Liver Transplantation
Lymphocyte Depletion
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Nude

Phenotype

Swine

Thymus Gland

Transplantation, Heterologous

Source

Open in PubMed

Identifiers

PMID: 9507740
DOI: 10.1111/j.1399-3089.1998.tb00015.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9507740-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice.PMID 9507740Read ↗

A single-cell analysis of thymopoiesis and thymic iNKT cell development in pigsSemantic proximity Read ↗

The late stage of T cell development within mouse thymus.Semantic proximity Read ↗

Allogeneic and xenogeneic lymphoid reconstitution in a RAG2−/−IL2RGy/− severe combined immunodeficient pig: A preclinical model for intrauterine hematopoietic transplantationSemantic proximity Read ↗

Two groups of porcine TCRgammadelta+ thymocytes behave and diverge differently.Semantic proximity Read ↗

The concurrent maturation of mouse and human thymocytes in human fetal thymus implanted in NIH-beige-nude-xid mice is associated with the reconstitution of the murine immune system.Semantic proximity Read ↗

Donor-reactive T cells and innate immune cells promote pig-to-human decedent xenograft rejectionSemantic proximity Read ↗

Prolonged xenokidney graft survival in sensitized NHP recipients by expression of multiple human transgenes in a triple knockout pigSemantic proximity Read ↗

Xenotransplantation: immunological hurdles and progress toward toleranceSemantic proximity Read ↗

Differentiation of CD4(high)CD8(low) coreceptor-skewed thymocytes into mature CD8 single-positive cells independent of MHC class I recognition.Semantic proximity Read ↗

Allogeneic CD4+CD25high T cells regulate obliterative bronchiolitis of heterotopic bronchus allografts in both porcinized and humanized mouse models.Semantic proximity Read ↗

Development of T cell receptor-gamma delta cells. Phenotypic and functional correlations of T cell receptor-gamma delta thymocyte maturation.Semantic proximity Read ↗

Subsets of rat CD4+ T cells defined by their differential expression of variants of the CD45 antigen: developmental relationships and in vitro and in vivo functions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.