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Article

Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice.

Xenotransplantation - 1 Feb 1998

Zhao Y, Barth R N, Swenson K, Pearson D A, Sykes M

Abstract excerpt

Mouse CD4+ T cells efficiently develop in fetal pig thymus (FP THY) grafts and repopulate the periphery of T cell and NK cell-depleted, thymectomized (ATX) mice. However, efficient peripheral repopulation of mouse CD8+ T cells does not occur in these mice. We have therefore evaluated the maturation and function of mouse CD8 single positive (SP) thymocytes in fetal pig thymus and liver fragment (FP THY LIV)...

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Identifiers

PMID: 9507740
DOI: 10.1111/j.1399-3089.1998.tb00015.x

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