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Article

Non-disjunction of chromosome 18

1 Apr 1998

Abstract excerpt

A sample of 100 trisomy 18 conceptuses analysed separately and together with a published sample of 61 conceptuses confirms that an error in maternal meiosis II (MII) is the most frequent cause of non-disjunction for chromosome 18. This is unlike all other human trisomies that have been studied, which show a higher frequency in maternal meiosis I (MI). Maternal MI trisomy 18 shows a low frequency of recombination...

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Identifiers

PMID: 9499419
DOI: 10.1093/hmg/7.4.661

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