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Article

Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line

1 Mar 1998

Abstract excerpt

BACKGROUND: The available human prostate cancer cell lines that are metastatic in athymic nude mice all have complex, highly aneuploid karyotypes. Other prostatic cells immortalized by transforming genes of SV40 or HPV and converted to tumorigenicity by additional genetic manipulation are not reported to be metastatic. METHODS: Tumorigenic sublines of human prostate epithelial cells previously immortalized by...

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PMID: 9496902
DOI: 10.1002/(sici)1097-0045(19980301)34:4<275::aid-pros5>3.0.co;2-g

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