Article
A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes.
International journal of oncology - 1 Oct 2004
Gu Yongpeng, Kim Kee-Hong, Ko Daejin, Nakamura Keiichiro, Yasunaga Yutaka, Moul Judd W, Srivastava Shiv, Arnstein Paul, Rhim Johng S
Abstract excerpt
Understanding of molecular genetic mechanisms underlying prostate carcinogenesis would be greatly advanced by in vitro models of prostate tumors representing primary tumors. We have successfully established a neoplastic immortalized human prostate epithelial (HPE) clonal culture derived from a primary tumor of a prostate cancer patient (RC-58T) with hTERT, the catalytic subunit of telomerase. The early passage...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
