Article
A new LexA-based genetic system for monitoring and analyzing protein heterodimerization in Escherichia coli.
Molecular & general genetics : MGG - 1 Jan 1998
Dmitrova M, Younès-Cauet G, Oertel-Buchheit P, Porte D, Schnarr M, Granger-Schnarr M
Abstract excerpt
Interactions between proteins affect a wide variety of biological processes, such as signal transduction and control of gene expression. In order to facilitate the study of protein-protein interactions we have developed a new method for specifically detecting the heterodimerization of two heterol...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Colorimetry
- Dimerization
- Escherichia coli
- Genes, Synthetic
- Genes, fos
- Genes, jun
- Genetic Techniques
- Leucine Zippers
- Molecular Sequence Data
- Operator Regions, Genetic
- Phenotype
- Protein Conformation
- Protein Multimerization
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-fos