CD44 Splice Variants as Prognostic Markers in Colorectal Cancer

doi:10.1080/00365529850166257

Article

CD44 Splice Variants as Prognostic Markers in Colorectal Cancer

1 Jan 1998

Abstract excerpt

BACKGROUND: Splice variants of CD44 play a causal role in the metastatic spread of pancreatic carcinoma in the rat. In previous studies we have shown that homologues of these CD44 isoforms (CD44v6) are overexpressed during colorectal tumorigenesis in man and that CD44v6 overexpression is associated with an unfavorable prognosis in this disease. In the present study we have assessed the prognostic significance of...

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