Article
p53 expression in Langerhans cell histiocytosis.
Journal of pediatric hematology/oncology - 1 Jan 2000
Weintraub M, Bhatia K G, Chandra R S, Magrath I T, Ladisch S
Abstract excerpt
PURPOSE: Langerhans cell histiocytosis (LCH) is a disorder of unknown etiology involving the proliferation and accumulation of cells with the phenotype of a bone marrow-derived antigen-presenting cell of the skin, the Langerhans cell. We have studied p53 expression, an element in the control of cell proliferation, to determine whether it plays a role in the pathogenesis of LCH. PATIENTS AND METHODS: LCH lesions...
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