Article
New insights into the pathogenesis of Langerhans cell histiocytosis.
Current opinion in pediatrics - 1 Feb 1997
de Graaf J H, Egeler R M
Abstract excerpt
Langerhans cell histiocytosis (LCH) is an enigmatic disease, usually occurring in the young. Despite the fact that clinical entities of the disease have been known for some time, the pathogenesis and etiology remain obscure. A major stride toward understanding LCH was taken when ultrastructural and immunohistochemical studies identified the "histiocytic" cells in LCH lesions to be members of the Langerhans...
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