Article
Immunohistochemical study of the abnormal cells in Langerhans cell histiocytosis (histiocytosis x).
Virchows Archiv. A, Pathological anatomy and histopathology - 1 Jan 1990
Ornvold K, Ralfkiaer E, Carstensen H
Abstract excerpt
The immunophenotypic properties of the abnormal cells in routine specimens from 16 cases of Langerhans cell histiocytosis (LCH) were examined. In five cases, cryostat sections were also available. The abnormal cells expressed a similar phenotype and were positive for HLA-DR, S-100 protein, peanut agglutinin (PNA), CD1a, CD4 and several macrophage-associated markers, including CD11c, CDw32 and CD68 (the latter...
Topics
- Adult
- Antigens, CD
- Biomarkers
- Bone and Bones
- Child
- Child, Preschool
- Female
- Histiocytosis, Langerhans-Cell
- Humans
- Immunohistochemistry
- Infant
- Lymph Nodes