Article
Genetic variability and linkage disequilibrium within the DP region in the CEPH families.
Human immunology - 1 Dec 1997
Moonsamy P V, Klitz W, Tilanus M G, Begovich A B
Abstract excerpt
A PCR-based SSO-assay has been developed to characterize the allelic polymorphism at the HLA-DPA1 locus. To validate the performance of this assay, 77 samples were typed side by side in a blinded fashion by the SSO assay and sequencing-based typing (SBT); 100% concordance was seen between the two methods. To address questions of genetic variability and linkage disequilibrium within the class II region, 478...
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