Article
Polymorphism in the regulatory regions of the HLA-DPB1 gene.
Human immunology - 1 Oct 1999
Varney M D, Gavrilidis A, Tait B D
Abstract excerpt
Nucleotide sequencing of approximately 400 basepairs upstream from exon 1 of the DPB1 gene and sequence specific oligonucleotide hybridisation identified eight nucleotide positions to be polymorphic which were in linkage disequilibrium (LD) with DPA1 and DPB1 alleles. Substitutions at two sites (-230 and -224) formed three genotypes (DP-PRO1-3). DP-PRO 1 was the most common genotype and was in LD with DPA1*0103,...
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