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Article

Molecular defects leading to human complement component C6 deficiency in an African-American family.

Clinical and experimental immunology - 1 Jan 1998

Zhu Z B, Totemchokchyakarn K, Atkinson T P, Volanakis J E

Abstract excerpt

Complement component C6 deficiency (C6D) was diagnosed in a 16-year-old African-American male with meningococcal meningitis. The patient's father and two brothers also had C6D, but gave no history of meningitis or other neisserial infection. By using exon-specific polymerase chain reaction (PCR)/single-strand conformation polymorphism as a screening step and nucleotide sequencing of target exons, we determined...

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Identifiers

PMID: 9472666
DOI: 10.1046/j.1365-2249.1998.00455.x
PMCID: PMC1904847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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