The molecular basis of C6 deficiency in the western Cape, South Africa.

doi:10.1007/s004390050858

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Article

The molecular basis of C6 deficiency in the western Cape, South Africa.

Human genetics - 1 Oct 1998

Hobart M J, Fernie B A, Fijen K A, Orren A

Abstract excerpt

Deficiency of the sixth component of human complement (C6) has been reported in a number of families from the western Cape, South Africa. Meningococcal disease is endemic in the Cape and almost all pedigrees of total C6 deficiency (C6Q0) have been ascertained because of recurrent disease. We have...

Topics

Base Sequence
Complement C6
Exons
Genetic Markers
Haplotypes
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
South Africa

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