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Article

Hepatic lipase activity is lower in African American men than in white American men: effects of 5' flanking polymorphism in the hepatic lipase gene (LIPC).

Journal of lipid research - 1 Jan 1998

Vega G L, Clark L T, Tang A, Marcovina S, Grundy S M, Cohen J C

Abstract excerpt

Plasma high density lipoprotein cholesterol (HDL-C) concentrations are higher in African American men than in white men, but the mechanism(s) responsible for this ethnic difference has not been elucidated. This study examined the relationship between hepatic lipase activity, plasma HDL-C concentr...

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Source

Identifiers

PMID: 9469601

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9469601-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Hepatic lipase activity is lower in African American men than in white American men: effects of 5' flanking polymorphism in the hepatic lipase gene (LIPC).PMID 9469601Read ↗

Three polymorphisms associated with low hepatic lipase activity are common in African Americans.Semantic proximity Read ↗

Body mass index and hepatic lipase gene (LIPC) polymorphism jointly influence postheparin plasma hepatic lipase activity.Semantic proximity Read ↗

Promoter polymorphisms of hepatic lipase gene influence HDL(2) but not HDL(3) in African American men: CARDIA study.Semantic proximity Read ↗

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Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.Semantic proximity Read ↗

Sources of variability in genetic association studies: insights from the analysis of hepatic lipase (LIPC).Semantic proximity Read ↗

Lipoprotein subclass and particle size differences in Afro-Caribbeans, African Americans, and white Americans: associations with hepatic lipase gene variation.Semantic proximity Read ↗

Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations.Semantic proximity Read ↗

Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults.Semantic proximity Read ↗

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