Article
The role of the different CD34 epitopes in detection and positive selection of CD34+ bone marrow and peripheral blood stem cells.
Scandinavian journal of immunology - 1 Jan 1998
Croockewit A J, Raymakers R A, Preijers F W, Vierwinden G, de Witte T J
Abstract excerpt
Positive selection of CD34+ cells is an attractive approach to reduce tumour cell contamination in bone marrow (BM) and peripheral blood progenitor cell (PBPC) autografts in malignancies not expressing CD34. All current selection methods use monoclonal antibodies (MoAbs) specific for the class I or class II CD34 epitopes, while for detection most investigators use class III MoAbs. Since the distribution of the...
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