Article
Oligonucleotide ligation assay for detecting mutations in the human immunodeficiency virus type 1 pol gene that are associated with resistance to zidovudine, didanosine, and lamivudine.
Journal of clinical microbiology - 1 Feb 1998
Edelstein R E, Nickerson D A, Tobe V O, Manns-Arcuino L A, Frenkel L M
Abstract excerpt
This report describes the detection of mutations in the pol gene of human immunodeficiency virus type 1 associated with resistance to zidovudine, didanosine, and lamivudine by genotyping by an oligonucleotide ligation assay specific codons in the pol gene amplified by PCR. Our studies demonstrate...
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