Article
Recombinational exchanges at the capsular polysaccharide biosynthetic locus lead to frequent serotype changes among natural isolates of Streptococcus pneumoniae.
Molecular microbiology - 1 Jan 1998
Coffey T J, Enright M C, Daniels M, Morona J K, Morona R, Hryniewicz W, Paton J C, Spratt B G
Abstract excerpt
Serotype 19F variants of the major Spanish multiresistant serotype 23F clone of Streptococcus pneumoniae have been proposed to have arisen by recombinational exchanges at the capsular biosynthetic locus. Members of the Spanish multiresistant serotype 23F clone and the serotype 19F variants were c...
Topics
- Base Sequence
- Crossing Over, Genetic
- DNA Fingerprinting
- DNA, Bacterial
- Drug Resistance, Multiple
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polysaccharides, Bacterial