Analysis of the 5' portion of the type 19A capsule locus identifies two classes of cpsC, cpsD, and cpsE genes in Streptococcus pneumoniae.

doi:10.1128/JB.181.11.3599-3605.1999

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Article

Analysis of the 5' portion of the type 19A capsule locus identifies two classes of cpsC, cpsD, and cpsE genes in Streptococcus pneumoniae.

Journal of bacteriology - 1 Jun 1999

Morona J K, Morona R, Paton J C

Abstract excerpt

Analysis of the sequence data obtained from the 5' portion of the Streptococcus pneumoniae type 19A capsular polysaccharide biosynthesis locus (cps19a) revealed that the first seven genes are homologous to the first seven genes in the type 19F (cps19f) locus. The former genes were designated cps19aA to -G and were 70 to 90% identical to their cps19f counterparts. Southern hybridization analysis of the cps loci...

Topics

Bacterial Capsules
Bacterial Proteins
Base Sequence
Blotting, Southern
Galactosyltransferases
Genes, Bacterial
Genetic Variation
Molecular Sequence Data
Molecular Weight
Open Reading Frames
Phylogeny
Polymerase Chain Reaction
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

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Identifiers

PMID: 10348877
DOI: 10.1128/JB.181.11.3599-3605.1999
PMCID: PMC93832

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Streptococcus pneumoniae