Article
Zinc uptake into fibroblasts is inhibited by probenecid.
Biochimica et biophysica acta - 5 Jan 1998
Chang C Y, Muga S J, Grider A
Abstract excerpt
Cellular zinc transport has not been fully characterized. The role of an anion carrier was investigated by treating normal human fibroblasts, and those carrying a mutation which affects zinc transport, acrodermatitis enteropathica (AE), with the anion carrier inhibitor, probenecid. Zinc uptake (2, 10, or 20 micromol 1(-1) 65zinc) was determined during initial rates of uptake (15 min) following treatment with 0,...
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