Article
The effect of the acrodermatitis enteropathica mutation on zinc uptake in human fibroblasts.
Biological trace element research - 1 Nov 1995
Vazquez F, Grider A
Abstract excerpt
The acrodermatitis enteropathica (AE) mutation affects intestinal zinc absorption. Our goal was to determine whether the AE mutation affects zinc uptake in human fibroblasts. Zinc uptake was determined during initial rates of uptake (10 min) following incubation in HEPES/saline buffer. Zinc uptake (from 0.25 to 1 microM) into normal fibroblasts was significantly greater than into the AE fibroblasts (p < 0.05). In...
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