Article
Thrombophilic genotypes in subjects with idiopathic antiphospholipid antibodies--prevalence and significance.
Thrombosis and haemostasis - 1 Jan 1998
Ames P R, Tommasino C, D'Andrea G, Iannaccone L, Brancaccio V, Margaglione M
Abstract excerpt
To evaluate the significance of common thrombophilic genotypes in subjects with idiopathic antiphospholipid antibodies (aPL) we determined the methylenetetrahydrofolate reductase C677-->T (MTHFR) and factor V A506-->G (FV Leiden) polymorphisms in 49 subjects with idiopathic aPL (57% of whom suffered spontaneous vein thrombosis), in 70 subjects with a history of spontaneous vein thrombosis and in 193 healthy...
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