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Article

Inherited DNA mutations contributing to thrombotic complications in patients with sickle cell disease.

American journal of hematology - 1 Dec 1998

Zimmerman S A, Ware R E

Abstract excerpt

Thrombosis may play an important role in the pathophysiology of certain complications of sickle cell disease (SCD), including stroke and avascular necrosis (AVN). Currently there is no laboratory or clinical parameter that can identify patients who are at highest risk of developing these thrombotic complications. We hypothesized that some patients with SCD have an inherited hypercoagulable state that results in...

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Source

Identifiers

PMID: 9840906
DOI: 10.1002/(sici)1096-8652(199812)59:4<267::aid-ajh1>3.0.co;2-w

Genes

SCD
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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