Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amyloid angiopathy in a Volga German family with Alzheimer's disease and a presenilin-2 mutation (N141I).

Annals of neurology - 1 Jan 1998

Nochlin D, Bird T D, Nemens E J, Ball M J, Sumi S M

Abstract excerpt

We report the neuropathological features in 6 members of a Volga German family with autosomal dominant Alzheimer's disease linked to chromosome 1 who had a presenilin-2 mutation (N141I). The most significant feature in this family was the presence of severe or moderately severe amyloid angiopathy in five family members with clinical dementia. The index case with the presenilin-2 mutation had late-onset dementia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alzheimer Disease
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Membrane Proteins

Share to Mutation

Share to Pedigree

Source

Identifiers

PMID: 9450781
DOI: 10.1002/ana.410430124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amyloid angiopathy in a Volga German family with Alzheimer's disease and a presenilin-2 mutation (N141I).PMID 9450781Read ↗

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.Semantic proximity Read ↗

Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation.Semantic proximity Read ↗

Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.Semantic proximity Read ↗

Identification of PSEN2 mutation p.N141I in Argentine pedigrees with early-onset familial Alzheimer's disease.Semantic proximity Read ↗

Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele.Semantic proximity Read ↗

Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaquesSemantic proximity Read ↗

Sporadic and Familial Cerebral Amyloid AngiopathiesSemantic proximity Read ↗

APOE gene polymorphism as a risk factor for cerebral amyloid angiopathy-related hemorrhage.Semantic proximity Read ↗

Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease.Semantic proximity Read ↗

Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy.Semantic proximity Read ↗

PSEN1 Compound Heterozygous Mutations Associated with Cerebral Amyloid Angiopathy and Cognitive Decline Phenotype.Semantic proximity Read ↗

Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.