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Article

Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3

1 Jan 1998

Abstract excerpt

The genes of the family of interferon (IFN) regulatory factors (IRF) encode DNA binding transcriptional factors that are involved in modulation of transcription of IFN and interferon-induced genes (ISG). The presence of IRF binding sites in the promoter region of IFNA and IFNB genes indicates that IRF factors recognizing these sites play an important role in the virus-mediated induction of these genes. We have...

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PMID: 9446577
DOI: 10.1074/jbc.273.5.2714

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