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Article

Genetic determinants responsible for acquisition of dengue type 2 virus mouse neurovirulence.

Journal of virology - 1 Feb 1998

Bray M, Men R, Tokimatsu I, Lai C J

Abstract excerpt

Studies conducted some 50 years ago showed that serial intracerebral passage of dengue viruses in mice selected for neurovirulent mutants that also exhibited significant attenuation for humans. We investigated the genetic basis of mouse neurovirulence of dengue virus because it might be directly...

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Source

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Identifiers

PMID: 9445071
DOI: 10.1128/JVI.72.2.1647-1651.1998
PMCID: PMC124649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9445071-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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