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Article

A commentary on 10 years of aldose reductase inhibition for limited joint mobility in diabetes.

Journal of diabetes and its complications - 1 Jan 2000

Eaton R P, Sibbitt W L, Shah V O, Dorin R I, Zager P G, Bicknell J M

Abstract excerpt

This investigation examines the clinical response to long-term treatment of the diabetic syndrome of limited joint mobility (LJM) using an aldose reductase inhibitor (ARI) in comparison to historical controls, and proposes a potential role of aldose reductase (AR) genotype and expression in the clinical response to ARI. Clinical parameters, including quantitative hand movement and electromyogram, were followed...

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PMID: 9442813
DOI: 10.1016/s1056-8727(97)00049-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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