Article
A structural scaffolding of intermediate filaments in health and disease.
Science (New York, N.Y.) - 23 Jan 1998
Fuchs E, Cleveland D W
Abstract excerpt
The cytoplasm of animal cells is structured by a scaffolding composed of actin microfilaments, microtubules, and intermediate filaments. Intermediate filaments, so named because their 10-nanometer diameter is intermediate between that of microfilaments (6 nanometers) and microtubules (23 nanometers), assemble into an anastomosed network within the cytoplasm. In combination with a recently identified class of...
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