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Estrogen receptor (ER) gene polymorphism may predict the bone mineral density response to raloxifene in postmenopausal women on chronic hemodialysis.

Renal failure - 1 Jan 2005

Heilberg Ita Pfeferman, Hernandez Eddy, Alonzo Evelyn, Valera Raquel, Ferreira Larissa Gorayb, Gomes Samirah Abreu, Bellorin-Font Ezequiel, Weisinger Jose R

Abstract excerpt

The estrogen receptor (ER) gene has been considered as a candidate genetic marker for osteoporosis, and PvuII and XbaI polymorphisms of the ERalpha gene have been associated with low bone mineral density (BMD). We investigated whether ER polymorphism could predict the response of BMD in 28 postmenopausal women on hemodialysis with marked osteopenia or osteoporosis, randomized to receive raloxifene, a selective...

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PMID: 15807179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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