Article
An unusual illegitimate recombination occurs in the linear-plasmid-encoded outer-surface protein A gene of Borrelia afzelii.
Microbiology (Reading, England) - 1 Dec 1997
Wang Jianhui, Masuzawa Toshiyuki, Li Muqing, Yanagihara Yasutake
Abstract excerpt
In this study, we describe an unusual illegitimate recombination in the linear-plasmid-encoded outer-surface protein A gene of Borrelia afzelii. A 96 bp DNA segment was deleted from the ospA structural gene of B. afzelii strain R9. The nature of the rearrangement suggested that it arose by a stra...
Topics
- Animals
- Antigens, Surface
- Bacterial Outer Membrane Proteins
- Bacterial Vaccines
- Base Sequence
- Borrelia
- Borrelia Infections
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Genetic Variation
- Humans
- Ixodes
- Lipoproteins
- Molecular Sequence Data
- Nucleic Acid Conformation
- Plasmids
- Polymerase Chain Reaction