Deletion of porA by recombination between clusters of repetitive extragenic palindromic sequences in Neisseria meningitidis.

doi:10.1128/IAI.67.6.2928-2934.1999

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Deletion of porA by recombination between clusters of repetitive extragenic palindromic sequences in Neisseria meningitidis.

Infection and immunity - 1 Jun 1999

van der Ende A, Hopman C T, Dankert J

Abstract excerpt

PorA is an important component in a vaccine against infection with Neisseria meningitidis. However, porA-negative meningococci were isolated from patients, thereby potentially limiting the role of PorA-mediated immunity. To analyze the mechanism by which the porA deletion occurred, the regions upstream and downstream of porA from three meningococcal strains (H44/76, H355, and 860183) were sequenced. The porA...

Topics

Base Sequence
DNA, Bacterial
Gene Deletion
Genetic Variation
Humans
Meningococcal Infections
Molecular Sequence Data
Multigene Family
Neisseria meningitidis
Porins
Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 10338501
DOI: 10.1128/IAI.67.6.2928-2934.1999
PMCID: PMC96602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics