Article
Deletion of porA by recombination between clusters of repetitive extragenic palindromic sequences in Neisseria meningitidis.
Infection and immunity - 1 Jun 1999
van der Ende A, Hopman C T, Dankert J
Abstract excerpt
PorA is an important component in a vaccine against infection with Neisseria meningitidis. However, porA-negative meningococci were isolated from patients, thereby potentially limiting the role of PorA-mediated immunity. To analyze the mechanism by which the porA deletion occurred, the regions upstream and downstream of porA from three meningococcal strains (H44/76, H355, and 860183) were sequenced. The porA...
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