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Article

HLA-DR class II associations with rubella vaccine-induced joint manifestations.

The Journal of infectious diseases - 1 Jan 1998

Mitchell L A, Tingle A J, MacWilliam L, Horne C, Keown P, Gaur L K, Nepom G T

Abstract excerpt

HLA class II (HLA-DR) frequencies were examined in relation to incidence of acute arthralgia or arthritis in 283 white women who had received RA27/3 rubella vaccine (n = 146) or placebo (n = 137) postpartum. Leukocyte DNA was molecularly typed for HLA-DRB1 gene expression. Univariate analysis revealed higher frequencies of DR2 (odds ratio [OR], 4.8; 95% confidence interval [CI], 1.2-18.8) and DR5 (OR, 7.5; 95%...

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Identifiers

PMID: 9419163
DOI: 10.1086/513807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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