Article
Polymorphisms in HLA-DPB1 are associated with differences in rubella virus-specific humoral immunity after vaccination.
The Journal of infectious diseases - 15 Mar 2015
Lambert Nathaniel D, Haralambieva Iana H, Kennedy Richard B, Ovsyannikova Inna G, Pankratz Vernon Shane, Poland Gregory A
Abstract excerpt
Vaccination with live attenuated rubella virus induces a strong immune response in most individuals. However, small numbers of subjects never reach or maintain protective antibody levels, and there is a high degree of variability in immune response. We have previously described genetic polymorphisms in HLA and other candidate genes that are associated with interindividual differences in humoral immunity to...
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