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Article

Estimation of the amount of DNA polymorphism when the neutral mutation rate varies among sites.

Genetics - 1 Dec 1997

Misawa K, Tajima F

Abstract excerpt

Knowing the amount of DNA polymorphism is essential to understand the mechanism of maintaining DNA polymorphism in a natural population. The amount of DNA polymorphism can be measured by the average number of nucleotide differences per site (pi), the proportion of segregating (polymorphic) site (s) and the minimum number of mutations per site (s*). Since the latter two quantities depend on the sample size, theta...

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Identifiers

PMID: 9409850
DOI: 10.1093/genetics/147.4.1959
PMCID: PMC1208360

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