Allele-specific suppression by formation of new protein-protein interactions in yeast.

doi:10.1093/genetics/147.4.1635

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Article

Allele-specific suppression by formation of new protein-protein interactions in yeast.

Genetics - 1 Dec 1997

Sandrock T M, O'Dell J L, Adams A E

Abstract excerpt

Yeast fimbrin is encoded by the SAC6 gene, mutations of which suppress temperature-sensitive mutations in the actin gene (ACT1). To examine the mechanism of suppression, we have conducted a biochemical analysis of the interaction between various combinations of wild-type and mutant actin and Sac6...

Topics

Actins
Alleles
Arabidopsis Proteins
Binding Sites
Membrane Glycoproteins
Microfilament Proteins
Mutagenesis
Saccharomyces cerevisiae

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