Article
Analysis of V(H) genes rearranged by individual B cells in dermal infiltrates of patients with mycosis fungoides.
Clinical and experimental immunology - 1 Dec 1997
Förste N, Gellrich S, Golembowski S, Rutz S, Audring H, Sterry W, Jahn S
Abstract excerpt
In patients with cutaneous T cell lymphomas such as mycosis fungoides B cells can frequently be detected in the lymphocytic dermal infiltrate. To analyse their immunoglobulin heavy chain gene repertoire, single B cells were obtained from tissue sections of two typical patients with mycosis fungoi...
Topics
- Amino Acid Sequence
- B-Lymphocytes
- Base Sequence
- Female
- Gene Rearrangement
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Variable Region
- Molecular Sequence Data
- Mutation
- Mycosis Fungoides
- Skin
- Skin Neoplasms