Article
Effect of ecNOS polymorphisms and coronary artery disease upon exhaled nitric oxide.
Journal of molecular medicine (Berlin, Germany) - 1 Mar 2002
Thomas S, Bruce C, Birkhead A, Wang L
Abstract excerpt
Exhaled nitric oxide (eNO) is thought to arise principally from the airway epithelium. NO regulates smooth muscle tone, and abnormal activity of NO synthase has been implicated in coronary artery disease (CAD). Polymorphisms of endothelial constitutive NO synthase (ecNOS) may affect NO generation and be associated with CAD. It was hypothesised that a polymorphism, such as the ecNOS intron 4 polymorphism...
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