Article
Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds.
The Journal of biological chemistry - 26 Dec 1997
Miller C A
Abstract excerpt
The human aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator protein (ARNT) were coexpressed in the yeast Saccharomyces cerevisiae to create a system for the study of this heterodimeric transcription factor. Specific transcriptional activation mediated by AHR/ARNT heterodimer, which is a functional indicator of receptor expression, was assessed by beta-galactosidase activity...
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